Constant exposure to various stressors are leading to an increase in immunocompromising health conditions (1). In this review, the authors discuss the role of herbal immunomodulators. Synthetic chemotherapeutic agents, which are widely available in the commercial market, may be highly efficacious, but most are immunosuppressive and exert many side effects. Numerous herbs used in ethnoveterinary medicine can be successfully employed as adjuvant rehabilitators to negate the deleterious effects of chemotherapeutics. Globally, many studies have been conducted on these herbs and have revealed unique active constituents that activate the innate immune system through the stimulation of macrophages and lymphocytes, and modulation of the cytokine profile, which leads to a state of alertness with a subsequent reduction in the incidence of infection.

References

(1) Tiwari R, et al. Herbal immunomodulators, a remedial panacea for the designing and developing effective drugs and medicines: Current scenario and future prospects. Curr Drug Metab. 2018; doi: 10.2174/1389200219666180129125436.