In this study, the polyphenols of various botanical therapies were analyzed for the treatment of rosacea (1). As a systematic review, many databases were searched and analyzed. The results showed that 6 studies met the inclusion criteria. Studies evaluated licochalcone, silymarin, Crystanthellum indicum extract, and quassia extract. The studies evaluated topical formations of polyphenols. The authors concluded that there is evidence polyphenols may be beneficial for the treatment of rosacea symptoms. Polyphenols appear to be most effective at reducing facial erythema and papule and pustule counts. Studies did have significant limitations.