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Warning: Use of sedative and anaesthetic in pregnancy and early childhood

December 22, 2017

Health Canada is advising Canadians and healthcare professionals that new safety warnings will be added to the product safety information of the following sedative and anesthetic drugs when they are used in early childhood and during pregnancy: Diprivan (propofol), Ketalar (ketamine), Sevorane (sevoflurane), Suprane (desflurane), Forane/Isoflurane USP (isoflurane), Ativan (lorazepam), midazolam, phenobarbital and thiopental. The Department conducted two reviews to assess the potential risk of adverse effects on the development of children’s brains when certain sedative and anesthetic drugs are used in pregnancy or in early childhood.