Recent literature has focused on the association of psoriasis with lower than normal or highly deficient vitamin D blood levels. This study investigated the controversial association between psoriasis and vitamin D levels ⁽¹⁾. From 2012 to 2014, 561 subjects were assessed, of which 170 had psoriasis, 51 had an autoimmune bullous, and 340 were healthy patients. Anagraphical data, 25(OH)D blood levels, and seasons of vitaminD levels assessments were recorded for each group.Vitamin D levels were significantly different among the 3 groups. Psoriatic patients had significantly lower serum levels of 25(OH)D (21.8 ng/mL) than healthy controls (34.3 ng/mL). Patients with bullous diseases showed the lowest vitamin D mean values (18.2 ng/mL). These results confirm the reduced vitamin D levels in psoriatic patients when compared to healthy controls, and provide new evidence regarding the association of vitamin D levels and psoriasis duration.