High-Dose Vitamin C and Chemo Combined for Cancer

2015-06-11 10:00:48

There is some evidence that high-dose intravenous vitamin C (IVC) could increase the effectiveness of chemotherapy. In this study, the researchers carried out a phase I-II safety, tolerability, pharmacokinetic and efficacy trial of IVC combined with chemotherapy in patients whose treating oncologist judged that standard-of-care of off-label chemotherapy offered less than a 33% likelihood of a meaningful response ⁽¹⁾. Fourteen patients were enrolled. IVC was safe and generally well-tolerated, although some patients experience transient adverse events during or after IVC infusion. The results suggest that chemotherapy was improved. Three patients experienced transient stable disease, increased energy and functional improvement. They conclude that this study neither proves nor disproves IVC’s value in cancer therapy, but it indicates a feasible way to evaluate it.