Ketoconazole, also known as Nizoral, Extina, Xolegel, and Kuric, is an antifungal used to treat a number of serious fungal infections, both internally and externally. A recent health alert has been issued by Health Canada and the manufacturers, Apotex Inc and Teva Canada Ltd, as a serious risk of fatal liver toxicity can occur with its oral use. Liver toxicity as well as death has occurred in otherwise healthy patients, those taking the recommended dose as well as in those taking this medication longer than 10 days. This risk is increased in those already at high risk of liver toxicity.

If you’re currently taking or recently finished a round of ketoconazole and have concerns make sure to speak to your healthcare provider. Those taking this medication and experiencing any of the following symptoms should seek immediate medical care: fatigue, loss of appetite, pain in stomach, vomiting, pale stool, dark urine and yellowing of the skin or whites of the eyes.