This study investigated the effects of locally injected vitamin C in the treatment of persistent gingival inflammation (1). Twenty adult patients with persistent chronic gingival inflammation were included in this study. The same dose of sterile vitamin C was injected in gingival tissues after the completion of phase I therapy. Gingival biopsies were taken after total resolution of inflammation. The results showed that there was great improvement of the injected sites with recall visits. The authors conclude that Vitamin C is an effective adjunctive treatment in reducing various degrees of chronic gingival inflammation.