Vitamin D and Depression

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Vitamin D and Depression

A growing body of literature has shown vitamin D to be a useful tool in the fight against depression, used alone or in combination with prescription antidepressant medications.^(1,2,3) A recent study randomized 42 patients with depression to one of two groups: fluoxetine (Prozac) alone, or Prozac plus vitamin D (1500IU per day) for eight weeks. Using the Hamilton Depression Rating Scale as the primary outcome measure the study showed that vitamin D plus Prozac worked better than Prozac alone to improve depression symptoms.⁽⁴⁾

References

1) Kjærgaard M, Waterloo K, Wang CE, Almås B, Figenschau Y, Hutchinson MS, Svartberg J, Jorde R. Effect of vitamin D supplement on depression scores in people with low levels of serum 25-hydroxyvitamin D: nested case-control study and randomised clinical trial. Br J Psychiatry. 2012 Nov;201(5):360-8.

2) Dean AJ, Bellgrove MA, Hall T, Phan WM, Eyles DW, Kvaskoff D, McGrath JJ. Effects of vitamin D supplementation on cognitive and emotional functioning in young adults--a randomised controlled trial. PLoS One. 2011;6(11):e25966.

3) Shipowick CD, Moore CB, Corbett C, Bindler R. Vitamin D and depressive symptoms in women during the winter: a pilot study. Appl Nurs Res. 2009 Aug;22(3):221-5.

4) Khoraminya N, Tehrani-Doost M, Jazayeri S, Hosseini A, Djazayery A. Therapeutic effects of vitamin D as adjunctive therapy to fluoxetine in patients with major depressive disorder. Aust N Z J Psychiatry. 2013 Mar;47(3):271-5.

Vitamin D and Depression

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