Based on a growing body of evidence implicating low vitamin D status in the development of cardiovascular disease, the authors hypothesized that in Canadian HIV-positive adults, low vitamin D concentration would be associated with increased subclinical vascular disease progression (1). In this study, they analyzed the association. The results showed mean progression was 0.027 mm/year. Only 13.3% of participants were vitamin D deficient (25(OH)D < 50 nmol/L), whereas 61.7% had a 25(OH)D exceeding the sufficiency threshold (75 nmol/L). The authors conclude that baseline vitamin D was associated with carotid intima-media thickness progression in this relatively vitamin D replete, predominately white and male, Canadian HIV-positive population.

References

(1) Huff H, et al. Vitamin D and progression of carotid intima-media thickness in HIV-positive Canadians. HIV Med. 2018;19(2):143-151.