Creatine is a naturally occurring substance often used in supplement form by many body builders to increase muscle mass. It has several mechanisms of action but it is well known to increase ATP in the body. A recently published study shows the promising use of this nutrient in Huntington, a disease that currently has no cure.^[1] The first clinical trail of its kind, researchers found high doses of creatine may have the potential to slow brain atrophy and in turn potentially slow disease progression. Dose of 15g used in the study was found to be well tolerated and safe for periods of up to 18months. Previous studies published have also found this supplement to be safe, and tolerable at high doses.^[2,3] In one a marker linked with oxidative injury to DNA was found to be decreased in the creatine group, a marker normally found elevated in Huntington disease.^[3]