A double-blind, placebo-controlled study was conducted to study the effectiveness of the specific bioactive collagen peptide (BCP) powder VERISOL® on eye wrinkle formation and stimulation of procollagen I, elastin and fibrillin biosynthesis in the skin. 114 women aged 45-65 years were randomized to receive 2.5 g of BCP or placebo (maltodextrin powder), once daily for 8 weeks, with 57 subjects being allocated to each treatment group. The products were taken orally by the subjects at home according to the instructions given by the investigator. The powder was to be dissolved in water or any other liquid. Subjects were prohibited from using skincare products, suntanning, saunas, making lifestyle changes, etc. Skin wrinkles were objectively measured in all subjects, before starting the treatment, after 4 and 8 weeks as well as 4 weeks after the last intake (4-week regression phase). The BCP group showed a statistically significant reduction of eye wrinkle volume (p <0.05) in comparison to the placebo group after 4 and 8 weeks (20%) of intake and a long-lasting effect after 4 and 8 weeks of discontinuing treatment, including a 65% increase in pro collagen type I, an 18% increase in elastin and a 6% increase in fibrillin.