This study evaluated the effect of zing and omega-3 supplements as an adjunct in the treatment of attention-deficit/hyperactivity disorder (ADHD) of children ^[1]. It was randomized, double-blind and conducted in 150 children aged 6-15 years old that diagnosed as new cases of ADHD. They were evaluated for 8 weeks. Patients received methylphenidate, as well as either placebo, zinc sulfate, or omega-3. Clinical improvements were measured every 2 weeks. The results showed that scores improved significantly in the zinc group compared to the control group in those that had attention-deficit disorder subtype of ADHD. In the omega-3 group, better clinical response was seen than other groups. There were no significant differences between the omega-3 group and the placebo group.