2021-06-09 16:17:45
There are several ovulation inducing drugs used in fertility treatments for patients with polycystic ovarian syndrome (PCOS). In this study, patients with PCOS were randomized to receive letrozole plus N-acetylcysteine (NAC) (intervention group) or letrozole alone. 317 patients were included in the study. The results revealed a 14.6% pregnancy rate in the intervention group vs. 7.5% in the control. These results indicate that patients with PCOS receiving letrozole plus NAC demonstrated a statistically significant fertility rate compared to the control group receiving letrozole alone.
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Teimouri, B., Mollashahi, S., Paracheh, M., & Farzaneh, F. (2021). Comparison of the effect of letrozole alone with letrozole plus n-acetylcysteine on pregnancy rate in patients with polycystic ovarian syndrome: A randomized clinical trial. International Journal of Women’s Health and Reproduction Sciences, 9(1), 75-79.