2021-06-09 16:21:47
In a meta-analysis 15 RCT’s were included examining the peri-operative care of colorectal cancer patients. The most used probiotic species included Lactobacilli (L. acidophilus, L. plantarum) and Bifidobacteria (B. longum) There was a trend towards lower rates of post-operative infectious and non-infectious complications with probiotics vs. placebo. Administration of probiotics also reduced bacterial translocation, maintained intestinal mucosal permeability, and resulted in better balance of beneficial to pathogenic microorganisms. Therefore, the administration of peri-operative probiotics could possibly minimize the risk of post-operative complications.
[collapse collapsed title=Reference] Pitsillides, L., Pellino, G., Tekkis, P., & Kontovounisios, C. (2021). The Effect of Perioperative Administration of Probiotics on Colorectal Cancer Surgery Outcomes. Nutrients, 13(5), 1451.